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56 results

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Page 1
SOD3 and IL-18 Predict the First Kidney Disease-Related Hospitalization or Death during the One-Year Follow-Up Period in Patients with End-Stage Renal Disease.
Liu YH, Chen YH, Ko CH, Kuo CW, Yen CC, Chen W, Chong KY, Chen CM. Liu YH, et al. Antioxidants (Basel). 2022 Jun 18;11(6):1198. doi: 10.3390/antiox11061198. Antioxidants (Basel). 2022. PMID: 35740095 Free PMC article.
Therefore, ESRD patients suffer more cardiovascular and hospitalization events than healthy people. This study aims to test the correlations between ROS, SOD3, IL-2, IL-6, and IL-18 and the first kidney disease-related hospitalization or death events in ESRD patient …
Therefore, ESRD patients suffer more cardiovascular and hospitalization events than healthy people. This study aims to test the correlations …
Kidney failure, arterial hypertension and left ventricular hypertrophy in rats with loss of function mutation of SOD3.
Guo H, Xu D, Kuroki M, Lu Z, Xu X, Geurts A, Osborn JW, Chen Y. Guo H, et al. Free Radic Biol Med. 2020 May 20;152:787-796. doi: 10.1016/j.freeradbiomed.2020.01.023. Epub 2020 Jan 21. Free Radic Biol Med. 2020. PMID: 31972339
Using a novel rat strain with loss-of-function mutation of SOD3 created by replacing glutamate 124 of SOD3 with aspartic acid (SOD3(E124D) rat strain), we determined the effect of SOD3 on renal function and blood pressure in Dahl/SS rats. ...The SOD …
Using a novel rat strain with loss-of-function mutation of SOD3 created by replacing glutamate 124 of SOD3 with aspartic acid …
Serum and urinary SOD3 in patients with type 2 diabetes: comparison with early chronic kidney disease patients and association with development of diabetic nephropathy.
Kuo CW, Chen HL, Tu MY, Chen CM. Kuo CW, et al. Am J Physiol Renal Physiol. 2019 Jan 1;316(1):F32-F41. doi: 10.1152/ajprenal.00401.2017. Epub 2018 Oct 10. Am J Physiol Renal Physiol. 2019. PMID: 30303710 Free article.
Extracellular superoxide dismutase 3 (SOD3), one member of the antioxidant defense system and a superoxide scavenger, has been noted to be downregulated in the kidneys of diabetic mice and is characterized by a heparin-binding domain that can anchor the protein to t …
Extracellular superoxide dismutase 3 (SOD3), one member of the antioxidant defense system and a superoxide scavenger, has been noted …
The effect of long-term dehydration and subsequent rehydration on markers of inflammation, oxidative stress and apoptosis in the camel kidney.
Ali MA, Abu Damir H, Ali OM, Amir N, Tariq S, Greenwood MP, Lin P, Gillard B, Murphy D, Adem A. Ali MA, et al. BMC Vet Res. 2020 Nov 23;16(1):458. doi: 10.1186/s12917-020-02628-5. BMC Vet Res. 2020. PMID: 33228660 Free PMC article.
BACKGROUND: Dehydration has deleterious effects in many species, but camels tolerate long periods of water deprivation without serious health compromise. The kidney plays crucial role in water conservation, however, some reports point to elevated kidney function tes …
BACKGROUND: Dehydration has deleterious effects in many species, but camels tolerate long periods of water deprivation without serious healt …
Impact of the ACE2 activator xanthenone on tacrolimus nephrotoxicity: Modulation of uric acid/ERK/p38 MAPK and Nrf2/SOD3/GCLC signaling pathways.
Azouz AA, Omar HA, Hersi F, Ali FEM, Hussein Elkelawy AMM. Azouz AA, et al. Life Sci. 2022 Jan 1;288:120154. doi: 10.1016/j.lfs.2021.120154. Epub 2021 Nov 17. Life Sci. 2022. PMID: 34800514
The beneficial effects of angiotensin-converting enzyme 2 (ACE2) on the kidney and other organs have been investigated in several studies, but its role in tacrolimus nephrotoxicity still needs to be elucidated. ...In addition, xanthenone reinforced antioxidant defense agai …
The beneficial effects of angiotensin-converting enzyme 2 (ACE2) on the kidney and other organs have been investigated in several stu …
Shenqi formula delayed Alzheimer's disease-like symptoms by skn-1 pathway in Caernorhabditis elegans.
Zhi D, Xu S, Zhang L, Li Y, Zhu H, Zhao C, Wang D. Zhi D, et al. J Ethnopharmacol. 2023 Nov 15;316:116741. doi: 10.1016/j.jep.2023.116741. Epub 2023 Jun 6. J Ethnopharmacol. 2023. PMID: 37290734
ETHNOPHARMACOLOGICAL RELEVANCE: Shenqi formula is composed of Codonopsis pilosula (Cp) and Lycium barbarum (Lb), and it is traditionally used for promoting qi and nourishing the spleen, liver and kidney. Cp and Lb have been reported to improve cognitive performance in APP/ …
ETHNOPHARMACOLOGICAL RELEVANCE: Shenqi formula is composed of Codonopsis pilosula (Cp) and Lycium barbarum (Lb), and it is traditionally use …
The role of manganese in morphogenesis and pathogenesis of the opportunistic fungal pathogen Candida albicans.
Wildeman AS, Patel NK, Cormack BP, Culotta VC. Wildeman AS, et al. PLoS Pathog. 2023 Jun 26;19(6):e1011478. doi: 10.1371/journal.ppat.1011478. eCollection 2023 Jun. PLoS Pathog. 2023. PMID: 37363924 Free PMC article.
As a result of low cellular Mn, the mutants exhibit impaired activity of mitochondrial Mn-superoxide dismutase 2 (Sod2) and cytosolic Mn-Sod3 but no defects in cytosolic Cu/Zn-Sod1 activity. Mn is also required for activity of Golgi mannosyltransferases, and smf12delta/del …
As a result of low cellular Mn, the mutants exhibit impaired activity of mitochondrial Mn-superoxide dismutase 2 (Sod2) and cytosolic Mn- …
Extracellular superoxide dismutase (SOD3): tissue-specific expression, genomic characterization, and computer-assisted sequence analysis of the human EC SOD gene.
Folz RJ, Crapo JD. Folz RJ, et al. Genomics. 1994 Jul 1;22(1):162-71. doi: 10.1006/geno.1994.1357. Genomics. 1994. PMID: 7959763
We have isolated and characterized over 10,000 bp of the human EC SOD gene (SOD3 or EC 1.15.1.1) and its 5'- and 3'-flanking regions. Human genomic Southern blot analysis supports the existence of a single gene, without evidence for pseudogenes. ...Adult heart, placenta, p …
We have isolated and characterized over 10,000 bp of the human EC SOD gene (SOD3 or EC 1.15.1.1) and its 5'- and 3'-flanking regions. …
Deciphering MMP9's dual role in regulating SOD3 through protein-protein interactions.
Gawargi FI, Mishra PK. Gawargi FI, et al. Can J Physiol Pharmacol. 2024 Mar 1;102(3):196-205. doi: 10.1139/cjpp-2023-0256. Epub 2023 Nov 22. Can J Physiol Pharmacol. 2024. PMID: 37992301
However, the mechanism by which MMP9, a secretory protein, influences the extracellular antioxidant superoxide dismutase-3 (SOD3) is not yet clear. To explore MMP9's regulatory impact on SOD3, we employed human embryonic kidney-293 cells, transfecting them wi …
However, the mechanism by which MMP9, a secretory protein, influences the extracellular antioxidant superoxide dismutase-3 (SOD3) is …
SOD1, but not SOD3, deficiency accelerates diabetic renal injury in C57BL/6-Ins2(Akita) diabetic mice.
Fujita H, Fujishima H, Takahashi K, Sato T, Shimizu T, Morii T, Shimizu T, Shirasawa T, Qi Z, Breyer MD, Harris RC, Yamada Y, Takahashi T. Fujita H, et al. Metabolism. 2012 Dec;61(12):1714-24. doi: 10.1016/j.metabol.2012.05.005. Epub 2012 May 25. Metabolism. 2012. PMID: 22632894 Free PMC article.
Increased glomerular superoxide levels were observed in SOD1(-/-)SOD3(+/+) and SOD1(-/-)SOD3(-/-) C57BL/6-Akita mice but not in SOD1(+/+)SOD3(-/-) C57BL/6-Akita mice. The SOD1(-/-)SOD3(+/+) and SOD1(-/-)SOD3(-/-) C57BL/6-Akita mice exhibited hig …
Increased glomerular superoxide levels were observed in SOD1(-/-)SOD3(+/+) and SOD1(-/-)SOD3(-/-) C57BL/6-Akita mice but not i …
56 results